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Cancer Res. 2014;74(13):3579?0. 12. Mizuno T, Suzuki N, Makino H, Furui T, Morii E, Aoki H, et al. Cancer stemlike cells of ovarian clear cell carcinoma are enriched in the ALDH-high population associated with an accelerated scavenging system in reactive oxygen species. Gynecol Oncol. 2015;137(2):299-305. 13. Yasuda K, Torigoe T, Morita R, Kuroda T, Takahashi A, Matsuzaki J, et al. Ovarian cancer
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Cancer Res. 2014;74(13):3579?0. 12. Mizuno T, Suzuki N, Makino H, Furui T, Morii E, Aoki H, et al. Cancer stemlike cells of ovarian clear cell carcinoma are enriched in the ALDH-high population associated with an accelerated scavenging system in reactive oxygen species. Gynecol Oncol. 2015;137(2):299-305. 13. Yasuda K, Torigoe T, Morita R, Kuroda T, Takahashi A, Matsuzaki J, et al. Ovarian cancer
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S through IGF1R signaling. Oncogene. 2014;33(30):3908?7. 15. Corominas-Faja B, Oliveras-Ferraros C, Cuyas E, Segura-Carretero A, Joven J, Martin-Castillo B, et al. Stem cell-like ALDH(bright) cellular states in EGFR-mutant non-small cell lung cancer: a novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin. Cell Cycle. 2013;12(21):3390?04. 16. Hessman
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Sion and Negative groups (p < 0.05, Kaplan-Meier). b High expression level of ALDH1 in tumor cells in ovarian carcinomas was significantly associated with high PFS probabilities (p < 0.05, Kaplan-Meier). c The expression level of ALDH1 in the stromal cells in ovarian carcinoma had no significant association with OS probabilities (p > 0.05, Kaplan-Meier). d No statistical association was found betw
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Sion and Negative groups (p < 0.05, Kaplan-Meier). b High expression level of ALDH1 in tumor cells in ovarian carcinomas was significantly associated with high PFS probabilities (p < 0.05, Kaplan-Meier). c The expression level of ALDH1 in the stromal cells in ovarian carcinoma had no significant association with OS probabilities (p > 0.05, Kaplan-Meier). d No statistical association was found betw
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Le survivals [24]. Similar results were obtained by immunofluorenscence-based and quantitative approach in Rimm's group from Yale University School of Medicine, a better prognosis in ALDH1(+) patients with non-small cell lung cancer, using the same primary antibody with us [39]. Thus, the choice of antibody may potentially explain the variably predictive and prognostic role of ALDH1 in human epith
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Le survivals [24]. Similar results were obtained by immunofluorenscence-based and quantitative approach in Rimm's group from Yale University School of Medicine, a better prognosis in ALDH1(+) patients with non-small cell lung cancer, using the same primary antibody with us [39]. Thus, the choice of antibody may potentially explain the variably predictive and prognostic role of ALDH1 in human epith
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Ulates retinoic acid signalling in mediating islet differentiation and survival. Diabetologia. 2014;57(4):754?4. 6. Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, et al. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res. 2009;69(8):3382?. 7. Moreb JS, Baker HV, Chang LJ, Am